SARS-CoV-2 Smoking Gun

We found that SARS-CoV has the restriction site fingerprint that is typical for synthetic viruses. pdf

The BsaI/BsmBI map of SARS-CoV-2 is anomalous for a wild coronavirus and more likely to have originated from an infectious clone designed as an efficient reverse genetics system. The research goals and laboratory logistics of infectious clone technology can leave a previously unreported fingerprint in the genomes of infectious clones. As a result of these constraints, published infectious clones have longest-fragment-lengths significantly shorter than those of natural CoVs digested by a range of restriction enzymes.


The preprint, released last week, argues that SARS-CoV-2, the virus that causes COVID-19, may have originated as a synthetic virus in the lab. It has not yet been peer reviewed or published in a scientific journal. post